Using today’s evidence to guide tomorrow’s decisions
Developing a cohesive value story from disparate pieces of evidence can be challenging. At best, it can be complicated when done well and, at worst, misleading when done poorly.
We partner with our clients to create and optimize models that answer complex questions and drive strategic decisions. We have extensive experience building health economics models that help our clients with critical business decisions and regulatory submissions.
Well-designed models frame the scope of how ‘value’ can be defined, summarize expected sources of value, identify evidence gaps, and inform strategic decision making.
Construct the framework from which value can be defined
Estimate the potential of novel therapies with limited evidence
Develop an understanding of disease-specific key value drivers
Identify vital evidence gaps in the value story
Estimate the impact of treatment decisions on health outcomes
Quantify impacts on cost of care and quality of life
Support regulatory submissions
Inform regulatory policy and treatment practice
Summarize costs associated with coverage decisions
Test uncertainty around patient populations
Provide a foundation for payer negotiations
Synthesize a broad array of evidence into controlled comparisons
Simulate a direct cohort study using available evidence
Identify comparative benefits of specific treatments when evidence is lacking or insufficient
Putting it in Context
From early-stage development to payer negotiations, Medicus’ modeling initiatives help to guide value demonstration throughout the product life cycle
Early-stage modeling provides crucial insights into the relative importance of evidence inputs and gaps. Developing early-stage models can also help to avoid pitfalls in value demonstration. Highlighting key drivers of value and crucial gaps can guide research strategy leading up to successful launch and beyond.
Lots of data is generated over the life cycle of a therapy. Modeling provides a single place to synthesize data using an organized structure. Modeling provides a key tool to quantify the impact of treatment on health outcomes and test key assumptions.
Increasingly, regulatory authorities and payers require robust models to support coverage decisions. Bulletproof models provide the foundation for successful negotiations and optimizing market opportunities.
Whether a scientific publication, payer tool, or health technology assessment, transparency in the construction, parameterization, and interpretation of models builds trust in the value story.
The Medicus Approach to
We draw on our extensive experience to build custom models specific to our clients’ needs. We lead and generate innovation in the field of value demonstration, both in terms of perspective and execution.
We work closely with our clients to understand the key questions and opportunities. Then, we tailor our models to provide answers that make a difference. Because we build custom models, they are not limited in the insights they can provide.
We ensure that your product's value story is communicated clearly to key stakeholders and decision makers throughout its journey to market and beyond.
Explore case studies with a focus on Modeling & Evidence Synthesis
How should payers think about the value of a first-in-class gene therapy?
What does emerging evidence tell us about early intervention in Alzheimer’s disease?